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Index > Protein center > GGCT(Gene name) > Human
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  • GGCT (Gene name),
  • Gamma-glutamylcyclotransferase (Protein name ),  GGCT_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    GGCT(C7orf24;CRF21);
    Protein name:
    Gamma-glutamylcyclotransferase;
    Alternative:
    Cytochrome c-releasing factor 21;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis. Induces release of cytochrome c from mitochondria with resultant induction of apoptosis.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    188
    Sequence:
    50:
    MANSGCKDVT | GPDEESFLYF | AYGSNLLTER | IHLRNPSAAF | FCVARLQDFK | 
    100:
    LDFGNSQGKT | SQTWHGGIAT | IFQSPGDEVW | GVVWKMNKSN | LNSLDEQEGV | 
    150:
    KSGMYVVIEV | KVATQEGKEI | TCRSYLMTNY | ESAPPSPQYK | KIICMGAKEN | 
    188:
    GLPLEYQEKL | KAIEPNDYTG | KVSEEIEDII | KKGETQTL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    String:
    SMR:
    MIM:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Gamma-glutamylcyclotransferase
    Cat.:
    E13744m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Gamma-glutamylcyclotransferase
    Cat.:
    E13744b
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Gamma-glutamylcyclotransferase
    Cat.:
    E13744h
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Gamma-glutamylcyclotransferase
    Cat.:
    U13744b
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Gamma-glutamylcyclotransferase
    Cat.:
    U13744m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Gamma-glutamylcyclotransferase
    Cat.:
    U13744h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Gamma-glutamylcyclotransferase
    Cat.:
    P13744Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Gamma-glutamylcyclotransferase
    Cat.:
    P13744Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Gamma-glutamylcyclotransferase
    Monoclonal Antibody for Human Gamma-glutamylcyclotransferase
    Monoclonal Antibody for Human Gamma-glutamylcyclotransferase
    Monoclonal Antibody for Human Gamma-glutamylcyclotransferase
    Protein for Human Gamma-glutamylcyclotransferase
    Protein for Human Gamma-glutamylcyclotransferase
    Protein for Human Gamma-glutamylcyclotransferase

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    Precision
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    Linearity
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    References
    1. 1.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Skeletal muscle.
    2. 2.
      "The DNA sequence of human chromosome 7."
      Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , more...
      Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Kidney.
      tissue: Lung.
      tissue: Skin.
      tissue: Urinary bladder.
    5. 5.
      "A novel 21-kDa cytochrome c-releasing factor is generated upon treatment of human leukemia U937 cells with geranylgeraniol."
      Masuda Y. , Maeda S. , Watanabe A. , Sano Y. , Aiuchi T. , Nakajo S. , Itabe H. , Nakaya K.
      Biochem. Biophys. Res. Commun.346:454-460(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY;FUNCTION;INDUCTION
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    7. 7.
      "The identification and structural characterization of C7orf24 as gamma-glutamyl cyclotransferase: an essential enzyme in the gamma-glutamyl cycle."
      Oakley A.J. , Yamada T. , Liu D. , Coggan M. , Clark A.G. , Board P.G.
      J. Biol. Chem.283:22031-22042(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS);IDENTIFICATION BY MASS SPECTROMETRY;FUNCTION;SUBUNIT;ACTIVE SITE;MUTAGENESIS OF GLY-23; GLU-98; TYR-105 AND TYR-125
    8. 8.
      "Crystal structure of Homo sapiens protein LOC79017."
      Bae E. , Bingman C.A. , Aceti D.J. , Phillips G.N. Jr.
      Proteins70:588-591(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.01 ANGSTROMS) OF 2-188;SUBUNIT
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